Error 522 on some images and js files, with Development mode turn-on it's ok, but how to fix for Dev Mode off?

Well, but with it being turned off it actually shouldnt work, should it? And it did load the site without issues.

Cant tell, you could only forward the connection IDs to Cloudflare and maybe they can dig out what the issue was.

That might be either an issue with your server configuration or alternatively a browser issue. There are no 522 in that list though.