DNS queries to 1.1.1.1 timing out

I have been managing a network and it appears something has recently begun blocking access to cloudflare dns servers 1.1.1.1 and family. The https://1.1.1.1 url is working but dns queries fail with timeout.

The issue seems to be limited to the windows based desktop computers, as i can perform queries on the linux based routers.

Dns queries to 8.8.8.8 on the other hand work fine, so it seems something is specifically blocking 1.1.1.1 / 1.0.0.1 / 1.1.1.2 / 1.1.1.3 on port 53

It seems unlikely that this is actually a cloudflare issue but since it seems to be a very specific issue i was hoping somebody might have a hint or other helpful information.