Can R2 and Images work together?

I want to get the resized image through URL parameter.
We know it’s possible with Cloudflare Images.
However, uploading images to Cloudflare Images and other types of files to R2 is not what I want.
I would like to easily manage the file upload function and the callbacks for it.
Can I use the features of Cloudflare Images for images of files registered to R2?