Can caching affect adsense revenue?

I activated page rule caching, I tried cache level: everything then I switched it to standard. Can caching impact adsense ad serving? change or misfunction anything about it? If content is cached content isn’t updated until you clear the cache, is anything like that about ads? It is obvious ads have their fixed javascript code and every singe ad is rendered in user’s browser, so can caching impact ads, clicks, and revenue? is it possible and real scenario?

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